The truth is, the amount of propylene glycol in hair loss treatments is not likely to cause any real harm and the FDA has given the chemical approval for many uses. But even though it is safe, we wanted to ensure that our top picks would be as comfortable to use as possible. So when Dr. Khadavi told us that “a third of my patients get irritated from minoxidil products because of propylene glycol,” we decided to cut any treatments with it. In any case, it’s the minoxidil that helps curb hair loss and not the propylene glycol.


Minoxidil was the first drug approved by the FDA for the treatment of male pattern baldness. For many years, minoxidil, in pill form (brand name Loniten), was widely used to treat high blood pressure. Just like finasteride, researchers discovered a very interesting side effect of the drug. People taking the medication were growing hair in unexpected places, such as on their cheeks and the back of their hands. Some people grew hair on their foreheads.
There are many potential causes of hair loss, including medical conditions, medications, and physical or emotional stress. If you notice unusual hair loss of any kind, it's important to see your primary care provider or a dermatologist, to determine the cause and appropriate treatment. You may also want to ask your clinician for a referral to a therapist or support group to address emotional difficulties. Hair loss can be frustrating, but recent years have seen an increase in resources for coping with the problem.
Defy hair loss with ROGAINE®, the #1 dermatologist-recommended, FDA-approved brand with a clinically proven formula to regrow hair. Unlike thickening shampoos that temporarily coat the hair, ROGAINE® penetrates deep into your scalp to revive follicles and increase protein production so you can grow new, fuller, thicker hair. The revolutionary formula begins to work on contact with patented Tricho-Prime™ Technology, a proprietary combination of ingredients that primes your scalp for optimal hair regrowth.
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I am a 30 year old woman, after my second child, I noticed that my hair was thinning on the top of my head, I had read it was normal for hair to thin and to loose hair while breast feeding and all that, but my daughter is now 18 months and did not see my hair come back to how it used to, so I decided to try this product. I have been using it for about 22 days and I do see the difference, it is not very thick as it used to but I hope with time using the product it will get better. I also see some hair growth, so far so good!! BTW, you need to apply it twice a day, it comes on liquid form and it is very easy to use.
Some women find that the minoxidil solution leaves a deposit that dries and irritates their scalp. This irritation, called contact dermatitis, is probably caused not by the minoxidil itself, but rather by the alcohol that is included to facilitate drying. A 5% solution (available only by prescription and approved only for men) is more effective than the 2% formulation and may be prescribed off-label for women. The 5% version comes in a foam, which appears to cause less irritation than the liquid.
While you won’t find a miracle shampoo on the market, nioxin and some other products can help keep your scalp in tip-top shape to improve the look of any hairs you do have left on your head. In fact, feeding your hair with the proper nutrients both inside and out can make it appear healthier, so you might consider using products with natural herbs, such as rosemary and mint.
The other main hair-loss treatment that was recommended by all four dermatologists I interviewed is finasteride, often called by its brand name Propecia. This FDA-approved medication is only available with a prescription, but these days, it’s found as a generic and ordered online after a virtual consultation, through start-ups like Hims, Keeps, and Lemonaid.
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