That said, there are products that don’t have FDA approval or clearance, but may help prevent hair loss. For example, shampoos with ketoconazole, a chemical with anti-DHT properties, is widely used to treat fungal infections but has become popular among consumers as a hair loss treatment. It makes sense — research shows that ketoconazole actually has beneficial effects on hair growth (especially for those with seborrheic dermatitis).
Also known as Rogaine, this over-the-counter (OTC) medication can be used for men or women with alopecia areata or androgenic alopecia. This drug comes in foam or liquid form and is spread on the scalp each day. It may cause more hair loss at first, and new growth may be shorter and thinner than before. You may also need to use it six months or more to prevent further loss and promote regrowth.
In either sex, hair loss from androgenetic alopecia occurs because of a genetically determined shortening of anagen, a hair's growing phase, and a lengthening of the time between the shedding of a hair and the start of a new anagen phase. (See "Life cycle of a hair.") That means it takes longer for hair to start growing back after it is shed in the course of the normal growth cycle. The hair follicle itself also changes, shrinking and producing a shorter, thinner hair shaft — a process called "follicular miniaturization." As a result, thicker, pigmented, longer-lived "terminal" hairs are replaced by shorter, thinner, non-pigmented hairs called "vellus."
Spironolactone, brand name Aldactone, is in a class of drugs called potassium-sparing diuretics (often called water pills). Spironolactone is typically used to reduce fluid in your body without causing the loss of potassium. It is also used to treat potassium deficiency, high blood pressure (hypertension), swelling (edema), and a hormonal disorder called hyperaldosteronism.
Like minoxidil, finasteride, the active ingredient in Propecia, was originally created with a different purpose in mind -- to treat enlarged prostate glands -- and researchers observed it came with a side effect of hair growth. Unlike topical minoxidil, finasteride requires a prescription, is taken orally and addresses hormonal causes of hair loss. It inhibits the enzyme type II 5-alpha reductase, which converts testosterone into DHT. As it was the first truly effective treatment for hair loss that provided nearly guaranteed results, finasteride revolutionized the hair-loss-treatment industry.
A few studies support the use of red ginseng, sometimes called panax ginseng (about $25), for hair regrowth. It can have an anti-apoptotic effect on the hair, Rogers says, meaning it slows cell death so hair follicles can grow for a longer period of time. But before taking any of these supplements, it’s important to consult your doctor; a lab test can confirm whether you need a particular supplement or if taking it will just be a waste of time and money.
This article is COMPREHENSIVE and sticks to the tried and tested (read scientifically proven) treatment methods. For me, if you’re suffering from pattern baldness, then the best chance you have is the Big Three. That said, it is worth potentially trying other, more natural, treatments if your hair loss isn’t aggressive and if you have an aversion to medicated products. I’m not talking about snake oil here. There are some treatments out there that, while not a primary treatment mode, can help to at least arrest hair loss in milder cases. As always with hair loss it’s a question of probabilities. I don’t think I’ve come across a product that works 100% of the time for 100% of the people. But the best chance undoubtedly comes with the FDA approved products to date. Also loved the future pipeline chart. Fantastic view of what will (hopefully) be more effective treatments in the future.
Fish oil contains omega-3 fatty acids that perform multiple functions when it comes to healing skin issues. Your scalp is an extension of your skin. When this skin is distressed, it affects your hair growth. When fish oil supplements are taken, this stress is taken away by the anti-inflammatory activity of the omega-3 fats. These fatty acids also ensure the healthy development of the skin’s various layers and also their hydration and nourishment (59, 60). Take fish oil supplements on a daily basis for healthy skin and hair growth. You can take cod liver oil supplements instead of the fish oil ones as they also contain the same omega-3 fatty acids (61).
To give yourself a hot oil treatment, massage the oil into your scalp, then apply it all the way to the ends of your strands. Pile your hair on top of your head, cover it with a shower cap, then blast your strands with a blow-dryer for 15 minutes. Feel free to jump in the shower and shampoo and condition as usual—you’ll notice softer strands instantly.
Am an Af/Am women 49y.o. almost 50 in a week. Anyway, last april, I removed a weave and saw that around the perimeter of my hairline the hair was so thin, it was virtually bald. I presumed it was due to the weave rubbing against my fine hair; but I later reviewed pictures over the past 8 years and saw how my hair had progressively thinned. My sister and mother confirmed that despite my youthful appearance, the hair thining was likely genetic. I am a can do kinda girl so I sought options. Was evening considering hair replacement "Bosley-style". Long story a little shorter, I boutht this Equate Hair Regrowth after reading just about all of the reviews. Worse thing that could happen was NOTHING, so I would be exactly where I was...thining disappearing hair at the edges. I have used the Equate Hair Regrowth since April 2013 and the hair has regrown around the perimeter and I couldn't be more pleased. I bought for my elder sister 56 y.o. and she had significantly more hair-loss, almost bald edges in fact; now she too has experienced regrowth and was so pleased she recommended it to my mother 74 y.o. and I bought it for her also (she will start applying by the end of the week). Highly recommend this product and note that I have also been taking biotin supplements since April 2013. So, buy Equate Hair Regrowth and biotin for best results. Price can't be beat. Excellent

From what I’ve seen and read they can be quite effective–but come with several risks (scarring and unnatural-looking hairline come to mind). I haven’t dwelled much into it, but basically got FUT (follicular unit transfer), FUE (follicular unit extraction) and DHI (direct hair implant)–which is the newest, similar to FUE, most costly and provides the best results in most cases.
"I recommend that everyone [with any hair loss] take finasteride," says Robert M. Bernstein, MD. Bernstein is associate clinical professor of dermatology at Columbia University and founder of the Bernstein Medical Center for Hair Restoration. "To patients who are younger,” he says, “I also recommend minoxidil. But the mainstay is finasteride. The data show that, over five years, it significantly retards hair loss in 85% of users."
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