Some doctors prescribe Avodart off-label (meaning to treat something other than illnesses or conditions listed on the drug's label) to patients suffering from male-pattern baldness. Dutasteride, the active ingredient in Avodart, like finasteride, is used to treat enlarged prostate glands, but it blocks both types of the enzyme that create DHT, instead of just one. Studies show that dutasteride is superior to finasteride in treating AGA, but it has yet to be approved by the FDA for that purpose.
In our research and our conversations with experts, one name kept popping up repeatedly: Rogaine. As the first topical brand FDA-approved to help regrow hair (all the way back in 1988), Rogaine benefits from more than 20 years of clinical trials and consumer feedback. Rogaine was the first brand to offer a 5 percent minoxidil foam solution when it debuted Men’s Rogaine Unscented Foam in 2006, and virtually every treatment developed since (for both men and women) has been an imitation or derivation of that formula.
Not surprisingly, treatments with 5 percent minoxidil work better than treatments with 2 percent minoxidil. A randomized clinical trial published in the American Journal of Clinical Dermatology in 2002 found that, in men with androgenetic alopecia, “5 percent topical minoxidil was clearly superior to 2 percent topical minoxidil and placebo in increasing hair growth.” The difference was actually pretty astounding — after 48 weeks, the men who used 5 percent minoxidil experienced 45 percent more hair growth than the men who used the 2 percent treatment.
Hair loss is no joke. People suffering from hairless often loose their self confidence. However, with the help of modern medicine, it is now possible to fight back. We hope that one of these products helps you in not only preventing hair loss but also to regrow your lost hair. So, what are you waiting for? Get one of these products and bid baldness adieu!!
Side effects and concerns: Around the time new hair growth starts, some women experience folliculitis (inflammation of the follicle). This minor complication can be treated with compresses and antibiotics. A more serious hazard is shock loss, the sudden loss of hair that normally grows in the area of the transplant. Shock loss affects 30% to 50% of female hair-transplant recipients; fortunately, the loss is usually temporary, and the hair will regrow. One drawback is that there's a finite amount of donor hair, and it may not be enough to fill in the transplant site as densely as before, especially if the area of thinning hair is large. A transplant procedure can cost from $4,000 to $15,000 and is rarely covered by insurance.
There’s no cure for baldness, but there are ways to hold on to what you've got. The six dermatologists and the clinical studies point to three methods: minoxidil, laser treatments, and prescription finasteride. The key is finding the combination and hair loss regimen that works for you. A doctor is your best bet for that kind of guidance — but we found a few trustworthy products that will work for most people.
During this procedure, surgeons remove a narrow strip of scalp and divide it into hundreds of tiny grafts, each containing just a few hairs. Each graft is planted in a slit in the scalp created by a blade or needle in the area of missing hair. Hair grows naturally this way, in small clusters of one to four follicles, called follicular units. As a result, the graft looks better than the larger "plugs" associated with hair transplants of yesteryear.
The second member of “the big three” and another extremely effective FDA approved hair loss treatment is minoxidil. Minoxidil was originally an oral medication for high blood pressure. But after a while, patients started reporting hair growth — all over their bodies. And not much longer after, the minoxidil topical solution for treating hair loss was born.
“I’m 43 years old and my hair has started to thin out a little bit. I started looking into a lot of these different products on the market that claim they can slow down balding in men and some of them even claim they can regrow your actual hair. As I went on the internet and started looking around, I kind of went down a rabbit hole into these different reviews and all sorts of different products from vitamins to topical solutions. Do any of these things do what they claim they can do?”
A commonly prescribed treatment for women is hormone replacement therapy (HRT). HRT is only prescribed to women with AGA during menopause or women who have low estrogen and/or progesterone for other reasons. These female hormones suppress male hormone production and seem to keep hair loss at bay. Physicians, however, do not recommend long periods of HRT treatment because of the increased risk of breast cancer, heart disease and stroke.
If you do decide to start treatment to save your hair, a good place to start is with minoxidil, more commonly known as Rogaine. Don’t expect this hair-loss treatment to create luscious locks; minoxidil is better at slowing down or preventing more loss rather than promoting hair growth. But, according to Dr. Amy McMichael, professor and chair of Wake Forest Baptist Medical Center’s Department of Dermatology, it is effective “if used as recommended, with evidence of improvement seen around six to nine months.” Simply massage the foam or solution into your scalp once or twice daily, and for best results, use a formula with 5 percent concentration.
"Others are taking hair follicles out of human scalp and growing them with dermal papilla cells," Cotsarelis says. "If they grow in culture, you might be able to recombine them with skin cells and form new follicles. This would let you expand the number of follicles you get for a hair transplant. This may not be that far off -- five to 10 years, maybe. There's very good evidence you will be able to do that."
But in November, after 10 years of research, Rogaine introduced a new 5 percent minoxidil formulation for women. It’s a mousse (instead of a liquid) that needs to be applied only once a day instead of twice, which means that it can be more easily incorporated into a woman’s evening skin-care routine. Teal replaces the blue and silver palette of the men’s Rogaine, and the packaging bears a lotus flower. (Also last year, Pantene introduced its Hair Regrowth Treatment for Women, which is 2 percent minoxidil.)
Just letting go is possibly the most challenging of the available options. It’s also the cheapest and ultimately the most effective in the struggle with hair loss. Given the imperfections of surgical, medical, and technological options, there are many who advocate simple acceptance. (BaldRUs.com is one of several sites devoted to embracing the scalp's natural fate.) What's more, the health benefits of happier mirror time -- and fewer years of harmful anxiety -- just might offset the loss of those Samson-like powers.