That meant new products like Hims and Keeps were out.Hims and Keeps are relatively new companies that allow you to set up a subscription for hair loss treatments. Both offer finasteride (after an online consultation with a doctor) or 5 percent minoxidil. However, their minoxidil solutions contain propylene glycol, so we cut them from consideration.
I have taken Propecia for 5 years. The first couple of years the side effects were minimal, but after they became more severe. Lacking morning wood, reduced ejaculate, reduced penile sensitivity are real issues. You’re be hard pressed to accuse some of suffering the nocebo effect in these instances. In which case you’re telling the person to just ignore the problems.
Other options include microneedling ($1,200 and up per treatment) and platelet-replacement therapy (also $1,200 and up per treatment), which are usually offered in conjunction. Your scalp will be numbed first so you don’t feel the pinpricks involved in microneedling. They promote hair regeneration by spurring wound healing, and platelet-replacement therapy involves injecting growth factors into those wounds. “Combination therapy typically works better than monotherapy and usually yields results after three monthly treatments,” says Sadick, and should be teamed with an at-home minoxidil treatment.
"This is an oral, prescription-only medication with the brand name Propecia that’s also FDA approved to treat hair loss," says Spencer. Male pattern hair loss occurs when a hormone called dihydrotestosterone (DHT) prevents hair follicles from getting the nutrients they need. Finasteride works by blocking the production of DHT, which protects the follicles.
“If you don’t want a scar because you like to wear your hair short, you might opt for a “scarless” hair transplant,” says Dr. Joyce. Also known as follicular unit extraction (FUE), grafts are harvested one at a time with tiny punches that heal virtually undetected so you can still buzz your head. “If you’ve gone so bald that you don’t have a lot of donor hair on your head, we can do FUE extractions with body hair such as on your chest, stomach, back, and sometimes even the pubic area,” says Dr. Joyce.
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Men may also experience some sexual and emotional side effects while taking it: In a study published in the June 2011 issue of The Journal of Sexual Medicine, Dr. Michael Irwig of George Washington University found as many as 92 percent of test subjects reporting problems in the bedroom. The study also reported that “the mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months,” meaning that side effects lingered long after subjects stopped taking the pill.
1. Minoxidil. It’s the only FDA-approved topical nonprescription medication that can claim to regrow hair — and it should be part of any hair-loss plan if you have serious thinning, says Rogers. Minoxidil has loads of research to back it, but it requires commitment. If you quit using it, your hair will start to lose ground again. Use a 5 percent strength, like Women’s Rogaine 5% Minoxidil Foam ($30), once daily to see results in three to four months, says Rogers.
3. Scalp tonic. Serums with peptides or procyanidins (a class of antioxidants) such as niacinamide can help support overall scalp health and reduce inflammation, which is a major component of hair loss, says New York City dermatologist Doris Day. Try René Furterer Triphasic Progressive Concentrated Serum ($82), Julien Farel Magnifique Delay the Gray Hair & Scalp Serum ($135), or Day’s own Rapid Regrowth Serum ($55) once daily before massaging a minoxidil product into the scalp (there’s no need to wait for it to dry in between). “In addition to being anti-inflammatory,” Day says, “scalp tonics help minoxidil penetrate the scalp better and can minimize potential irritation from it.”
4. Tinted dry shampoo. Camouflage spots where you’re seeing more scalp than you want to (your hairline, a widening part, a thinning crown) and add volume with a colored dry shampoo (try Orlando Pita Color Boost Dry Shampoo in Light or Dark Tones, $22). But be sure to give your scalp a vigorous shampoo during your next shower — dermatologists recommend keeping your scalp free of styling products so you’re not clogging already taxed pores.

Retin-A, or topical tretinoin, is sometimes used as a combination therapy with minoxidil for androgenic alopecia. It’s important to use this type of medication under the guidance of your doctor. In some circumstances, tretinoin can actually cause hair loss. Some people who have used it at home report that topical retinol creams, serums, and lotions may make hair loss worse.


Men may also experience some sexual and emotional side effects while taking it: In a study published in the June 2011 issue of The Journal of Sexual Medicine, Dr. Michael Irwig of George Washington University found as many as 92 percent of test subjects reporting problems in the bedroom. The study also reported that “the mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months,” meaning that side effects lingered long after subjects stopped taking the pill.
I'll start by saying I actually don't have a serious hair loss problem. However, I have always had calics along my hairline, so I wanted to fill them in a little before my sister's wedding. I started using this product about a month ago. I hate that it never seems to dry, so I ended up throwing my hair in a slick bun to hide the sticky look on a number of occasions. But just last week a coworker pointed out that my hairline was filling in, which is when I finally realized that it was working! The wedding is over, but I plan on using it over the course of the next three months to see if I can obtain more permanent results. So far I'm pleased, but the results take time and it's a little pricier than I would like to admit. The twice a day thing is kind of a pain in the arse.

Like minoxidil, finasteride, the active ingredient in Propecia, was originally created with a different purpose in mind -- to treat enlarged prostate glands -- and researchers observed it came with a side effect of hair growth. Unlike topical minoxidil, finasteride requires a prescription, is taken orally and addresses hormonal causes of hair loss. It inhibits the enzyme type II 5-alpha reductase, which converts testosterone into DHT. As it was the first truly effective treatment for hair loss that provided nearly guaranteed results, finasteride revolutionized the hair-loss-treatment industry.

The truth is, the amount of propylene glycol in hair loss treatments is not likely to cause any real harm and the FDA has given the chemical approval for many uses. But even though it is safe, we wanted to ensure that our top picks would be as comfortable to use as possible. So when Dr. Khadavi told us that “a third of my patients get irritated from minoxidil products because of propylene glycol,” we decided to cut any treatments with it. In any case, it’s the minoxidil that helps curb hair loss and not the propylene glycol.


The Rogaine rep we spoke to explained that the different packaging (and therefore different prices) has to do with the FDA-approval process: “We discovered in clinical trials that the hair loss patterns between men and women are different,” she said by way of explanation. “Men typically have that bald spot on the crown of their head, where women generally have a general thinning throughout, but concentrated more on the top of the head. So for FDA approval, we had to come up with two different, gender-specific products, so the directions were more explanatory.”

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Laser treatments are the latest frontier in staving off hair loss, and they’ll be the first choice for fans of sci-fi. As silly as they may sound, these treatments do work — the American Journal of Clinical Dermatology in 2014 reported a “statistically significant difference” in hair density with no “serious adverse events” or side effects.The bad news: Laser treatments tend to be expensive, progress is slow, and they don’t always produce stellar results.
It may seem a peculiar American vanity that men have in-boxes full of hair loss treatment offers and spend billions of dollars on hair loss treatments each year. Not so. As Gersh Kuntzman illustrates in his book Hair! Mankind's Historic Quest to End Baldness, chrome-dome anxiety has tormented us for ages. Caesar's laurel wreaths? Classic red herring, Kuntzman says.
Viviscal is a natural hair-growth supplement that promotes hair growth in people with thinning hair. It contains a marine complex known as AminoMar C. This is made of minerals, vitamins, and shark and mollusk powder. These ingredients help to regenerate new cells and strengthen existing cells. You have to take the pills twice a day for at least six months in order to see results. Viviscal also makes a shampoo and conditioner.
Great article thx!! I’m 38 and still have a full head of hair but I started to shed about 3 months ago. Typically ~15 hairs on my pillow when I wake up and 20 or so hairs on my hand after I shower. I also notice hairs on my desk during the day. I never noticed any hair loss before 3 months ago. I started to use rogaine 5% twice a day about a month and a half ago and the shedding accelerated. I read that is normal but should it still be doing this after 1.5 months? I haven’t tried propecia yet as I want to see if Rogaine will do the trick but will if the shedding doesn’t stop. Also, do you think stress can play a part in hair loss? I started a super stressful job about 6 months ago so thinking my hair loss could be related to that.
Cimetidine, brand name Tagamet, belongs to a class of histamine blockers used mainly to treat gastrointestinal ulcers. The histamine-blocking action prevents the stomach from producing excess acid, allowing the body to heal the ulcer. Cimetidine also has a fairly powerful anti-androgenic effect and has been shown to block dihydrotestosterone from binding the follicle receptor sites.
The comment about Dutasteride causing more side effects is not correct. All studies performed to this date actually sight that Dutasteride has lower side effects. Especially in regards to decreases in sex drive. The only time Dutasteride has been shown to have greater side effects is when the dosage of Finasteride was well below the recommended dosage of 1mg. In comparison 500mcg of Dutasteride has been shown to be more effective than 2.5mg of Finasteride and 1mg has shown to be more effective than 5mg of Finasteride, the dose used to treat BPH. The research has clearly shown that Dutasteride reduces serum DHT levels much faster and has much higher success rates.
The most common kind of hair loss is pattern baldness. It happens when hair follicles shrink and stop working. The first sign is the appearance of strands that are thinner and more fragile. Then the scalp becomes more visible as fewer hairs grow to replace those that shed. That’s because the anagen phase becomes too short for the hair to grow out of the scalp. Plus, the hairs that remain aren’t securely anchored. And this condition happens to both men and women.
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